Flexeril and hydrochlorothiazide metoprolol Interactions

Flexeril and hydrochlorothiazide metoprolol Interactions

It works by acting in the brain and nervous system to allow the muscles to relax. Although rare, deaths may occur from overdosage flexeril.live with FLEXERIL. Multiple drug ingestion (including alcohol) is common in deliberate cyclobenzaprine overdose.

Combining any of these drugs with alcohol or other depressants (including antihistamines, narcotics and some dental anesthetics) can make side effects more severe. Also, many of the medicines used to treat fibromyalgia work by boosting the amount of serotonin in your body. Taking two or more of these drugs together could lead to a potentially life-threatening condition called serotonin syndrome. Symptoms usually begin within hours of combining the drugs and include confusion, agitation, irregular heartbeat, unstable blood pressure, tremors, muscle rigidity, nausea and vomiting. If you have these symptoms, stop taking your medication and seek immediate medical help.

  • The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs.
  • Therefore, this drug should only be used in pregnancy if clearly needed.
  • Use of FLEXERIL for periods longer than two or three weeks is not recommended.
  • This weight gain is thought to be attributed to a period of physical inactivity caused by muscle relaxant use.

Prolonged use can lead to increased tolerance and physical dependence, especially with Soma.3 For this reason, muscle relaxers are intended as a short-term treatment not to be prescribed for more than 2-3 weeks. Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. These factors may affect how you should use this medication. The usual adult dose of cyclobenzaprine is 10mg 3 times a day, with a range of 20 mg to 40 mg a day (given in divided doses).

Alcohol interaction

Flexeril is used to treat skeletal muscle conditions such as pain, injury, or spasms in conjunction with rest and physical therapy. Prescription use of Cyclobenzaprine subjected to the supervision of a licensed doctor is most commonly linked with a non-emergent, tolerable adverse reaction. These reactions develop in ≥3% of the patients and consist of xerostomia, drowsiness, and dizziness all connected to the anticholinergic effects of cyclobenzaprine drug class.

In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement following both treatments was comparable. In a pharmacokinetic study of sixteen subjects with hepatic impairment (15 mild, 1 moderate per Child-Pugh score), both AUC and Cmax were approximately double the values seen in the healthy control group. Based on the findings, FLEXERIL should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of FLEXERIL in subjects with moderate to severe impairment is not recommended. Concomitant use of monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation.

Tell your doctor if you are pregnant or plan to become pregnant during treatment with Flexeril. It is unknown if Flexeril passes into breast milk or if it could harm a nursing baby. Addiction Resource does not offer medical diagnosis, treatment, or advice. Only trained and licensed medical professionals can provide such services. If you or anyone you know is undergoing a severe health crisis, call a doctor or 911 immediately.

Cyclobenzaprine and cost: Generics vs. brand name – Medical News Today

Cyclobenzaprine and cost: Generics vs. brand name.

Posted: Fri, 21 Apr 2023 21:53:11 GMT [source]

No one should assume the information provided on Addiction Resource as authoritative and should always defer to the advice and care provided by a medical doctor. He has a particular interest in psychopharmacology, nutritional psychiatry, and alternative treatment options involving particular vitamins, dietary supplements, and administering auricular acupuncture. Both of these drugs work to treat fibromyalgia pain and decrease muscle spasms. It’s believed to work by attaching to a receptor or protein in the brain called the alpha-2 receptor, which reduces the release of substance P in your brain and spinal cord. Substance P is a chemical that helps increase pain signals to and from the brain. Flexeril is a muscle relaxant that is commonly prescribed to treat pain and discomfort caused by muscle injuries.

What Causes Pain in the Trapezius Muscle?

If someone has taken an overdose of this medicine and has serious symptoms such as trouble breathing, seek medical advice immediately. Never take more doses than what is prescribed to you by your doctor. Flexeril has active ingredients of cyclobenzaprine hydrochloride.

Some people may not require a supervised detox program and will be able to undergo treatment on an outpatient basis. The recommended dose of immediate-release cyclobenzaprine is 5 to 10mg, three times a day, while that for extended-release versions is 15 to 30 mg, once a day. Maximum daily dose for either form is 30 mg over the course of 24 hours.

Common Cyclobenzaprine Side Effects

There is also a slight risk that abuse of Cyclobenzaprine or Flexeril can lead to serotonin syndrome. Serotonin syndrome occurs when you take medications that cause an excess of serotonin in your system. HydroCHLOROthiazide and cyclobenzaprine may have additive effects in lowering your blood pressure.

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